التفاصيل البيبلوغرافية
| العنوان: |
Metastatic Cutaneous Melanoma: Navigating the Evolving Treatment Landscape. |
| المؤلفون: |
Simon, Audrey C., Elder, Christopher T., Gyori, Derek J. |
| المصدر: |
Journal of Hematology Oncology Pharmacy; Feb2024, Vol. 14 Issue 1, p34-41, 8p |
| مصطلحات موضوعية: |
ADVERSE health care events, MELANOMA, CANCER treatment, INTERPROFESSIONAL collaboration, CANCER chemotherapy, PATIENT preferences |
| مستخلص: |
BACKGROUND: Pharmacotherapeutic approaches for cutaneous melanoma have shifted dramatically In the past decade, from traditional cytotoxic chemotherapy to single-agent targeted therapy, immunotherapy, and various drug combinations. As treatment options expand and the sequencing of treatments change, clinicians encounter complex decisions that impact melanoma regimen selection and management. Because of the evolving landscape and the expanding literature on metastatic melanoma, recognizing patient preferences, treatment options, and therapy-specific considerations will be key to optimizing patient care. OBJECTIVE: To provide a detailed overview of metastatic cutaneous melanoma, the current guideline recommendations, the emerging treatment strategies, and pharmacists' roles in the management of adherence and adverse events. DISCUSSION: This article provides practitioners with clinical trial information to aid in the understanding of treatment strategies in clinical practice settings. Several factors that influence decision-making in the selection of appropriate therapy will be analyzed, thus guiding practitioners in the decisions on front-line therapy. A pharmacotherapy monitoring chart for the current guideline-supported treatment can assist in recognizing and responding to issues that may arise during treatment. CONCLUSION: The future of melanoma treatment is bright with options aimed at overcoming treatment resistance and addressing treatment gaps. Interprofessional collaboration continues to remain essential in providing high-quality cancer care. Pharmacists' roles on the interprofessional oncology care team may expand as therapy becomes more complex. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
