التفاصيل البيبلوغرافية
| العنوان: |
PHENOLIC COMPOUNDS OF RHUS GLABRA. |
| المؤلفون: |
ABDULLADJANOVA, N. G., MAVLONOV, G. T., MAMADRAHIMOV, A. A., RAKHIMOV, R. N., NING, H., WALI, A., YILI, A., ABDULLA, R. |
| المصدر: |
Journal of Research in Pharmacy; 2023 Supplement, Vol. 27, p52-53, 2p |
| مصطلحات موضوعية: |
PHENOLS, BIOORGANIC chemistry, PHENOLIC acids, POLYPHENOLS, PLANT polyphenols, CHEMICAL structure, ETHYL acetate |
| مصطلحات جغرافية: |
UZBEKISTAN |
| مستخلص: |
Among the natural compounds representing medicinal benefits significant place belong to plant phenolics. A wide range of biological action and low toxicity allows include them in a number of promising medicinal formulations in this regard. Therefore, the search for plants containing phenolics, the development of methods for their isolation, the determination of their chemical structure, and the study of biological activity is an actual problem in bioorganic chemistry. In this regard, the aimof our study is study the chemical composition of the polyphenols of the Rhus glabra(Smooth sumac) plant, in order to search for new sources of raw materials rich in biological active compounds growing on the territory of the Republic of Uzbekistan. The leaves of R.glabra were collected at the end of the vegetative period, air dried in the shade. 70% aqueous acetone used for full extraction of phenolics, afterevaporation of acetone under vacuum, the aqueous residue sequentially partitioned with chloroform and ethyl acetate. Ethyl acetate fraction, containing main amount of phenolics (controlled by Folin-Ciocalteu's reagent) vacuum concentrated as far as possible and pool of phenol compounds precipitated by adding of chloroform. The yield of total phenolics was 12% of the air-dry weight of the raw material. Qualitative reactions and TLC methods revealed the presence of flavonols, phenolic acids and tannins in the composition of the total polyphenols. RP-HPLC with corresponding standards and LCMS/MS shown, that the main constituent of prepared phenolic fraction there was a group of the hydrolysable tannins - poly galloyl glucose. In Table below listed the identified compounds. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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