التفاصيل البيبلوغرافية
| العنوان: |
A Fatal Case of Presumptive Diagnosis of Leptospirosis Involving the Central Nervous System. |
| المؤلفون: |
Alexopoulou, Christina, Proklou, Athanasia, Kokkini, Sofia, Raissaki, Maria, Konstantinou, Ioannis, Kondili, Eumorfia |
| المصدر: |
Healthcare (2227-9032); Mar2024, Vol. 12 Issue 5, p568, 11p |
| مصطلحات موضوعية: |
LEPTOSPIROSIS diagnosis, LEPTOSPIROSIS, BLOOD testing, RETINAL degeneration, PURPURA (Pathology), BRAIN, COMPUTED tomography, CENTRAL nervous system, FEVER, HOSPITAL emergency services, GLASGOW Coma Scale, MAGNETIC resonance imaging, INTENSIVE care units |
| مستخلص: |
Leptospirosis is a reemerging zooanthroponosis with a worldwide distribution, though it has a higher incidence in areas with tropical climate. A characteristic finding of the disease is its wide spectrum of symptoms and organ involvement, as it can appear either with very mild flu-like manifestations or with multiorgan failure, affecting the central nervous system (CNS) with a concomitant hepatorenal dysfunction (Weil's syndrome) and significant high mortality rate. We report herein a fatal case of a 25 years old female, previously healthy, with impaired neurological status. She had high fever and severe multiorgan failure. The clinical data and the epidemiological factors were not conclusive for the diagnosis, and the first serology test from the cerebrospinal fluid (CSF) and sera samples were negative. When the repetition of the blood test showed elevated IgM antibodies, Leptospirosis was the presumptive diagnosis. Although CNS involvement is rare, the diagnosis should be considered when there is an elevated risk of exposure. The diagnostic protocol should encompass direct evidence of the bacterium and indirect measurement of antibodies. Timely detection and management are imperative to forestall complications and fatality associated with the disease. [ABSTRACT FROM AUTHOR] |
|
Copyright of Healthcare (2227-9032) is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder