دورية أكاديمية

Caloric Restriction and Intermittent Fasting: possible strategies for delaying brain aging in humans and animals.

التفاصيل البيبلوغرافية
العنوان: Caloric Restriction and Intermittent Fasting: possible strategies for delaying brain aging in humans and animals.
المؤلفون: A., Singh, S., Bhoumik, S. I., Rizvi
المصدر: Progress in Health Sciences; 2023, Vol. 13 Issue 2, p82-91, 10p
مستخلص: Calorie restriction (CR) is the strategy that has demonstrated a significant impact on slowing the biological rate of aging and increasing both average and maximum longevity in a variety of animals. A diet plan known as intermittent fasting (IF) calls for eating habits that involve prolonged periods of low or no-calorie intake. The morphology, architecture, vasculature, and cognition of the brain are known to change as the organism ages. Oxidative stress plays a crucial role in the aging of the brain. The effects of oxidative stress include mitochondrial dysfunction, protein modification, membrane lipid peroxidation, nuclear DNA oxidation, and mitochondrial and mitochondrial DNA oxidation. These effects hasten brain aging, neuronal loss, and cognitive impairment. Cognitive ability, long-term memory, and dementia are improved by CR and IF, which are beneficial for brain and neurodegenerative illnesses. The presented review article explores recent findings on how two dietary approaches, CR and IF, can support healthy aging and improve brain function. We will also explore how the most studied CR mimetics affect aging and how they might be used as treatments to promote neuroprotection. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index