التفاصيل البيبلوغرافية
| العنوان: |
Antidiabetic Activity of Bengkuang (Pachyrhizus erosus) Extracts in Diabetes Mellitus-induced Rats. |
| المؤلفون: |
Panjaitan, Ruqiah Ganda Putri, Anggraini, Putri, Raharjeng, Anita Restu Puji, Wansadaj Jaroenram |
| المصدر: |
Pertanika Journal of Tropical Agricultural Science; Feb2024, Vol. 47 Issue 1, p1-9, 9p |
| مصطلحات موضوعية: |
INDIGENOUS peoples of Mexico, HYPOGLYCEMIC agents, BLOOD sugar, RATS, DIABETES, NICOTINAMIDE, ALKALOIDS |
| مستخلص: |
Bengkuang (Pachyrhizus erosus) is in the pea family (Fabaceae) and is a native Mexican vine that produces an edible tuber called jicama or Mexican turnip in English. This study evaluated the antidiabetic activity of bengkuang extracts administered via oral gavage into rats at 4 days post-induction of streptozotocin-nicotinamide-induced diabetes mellitus. At 14 days post injection (daily) of extracts at 28 and 56 mg/200 g body weight (BW), blood glucose levels were significantly reduced (p < 0.05) from 277 ± 4 milligrams per deciliter (mg/dl) for the Diabetes Control Group to 182 ± 3 and 99 ± 55 mg/dl, respectively. The latter glucose level was comparable to that in the Antidiabetic Control Group rats (111 ± 63 mg/dl) injected with glibenclamide at 0.09 mg/200 g BW. The diabetes-induced rats also showed signs of cell recovery from diabetic-associated pancreatic tissue damage, supporting the efficacy of bengkuang treatment. According to phytochemical tests, the bengkuang extract contained various metabolites, mainly alkaloids and flavonoids, that may have been responsible for its antidiabetic activity. The results justify further studies on the underlying mechanisms of bengkuang antidiabetic activity. [ABSTRACT FROM AUTHOR] |
|
Copyright of Pertanika Journal of Tropical Agricultural Science is the property of Universiti Putra Malaysia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder