التفاصيل البيبلوغرافية
| العنوان: |
Spidroin‐mimetic Engineered Protein Fibers with High Toughness and Minimized Batch‐to‐batch Variations through β‐sheets Co‐assembly. |
| المؤلفون: |
Qin, Dawen, Wang, Mengyao, Cheng, Wenhao, Chen, Jing, Wang, Fan, Sun, Jing, Ma, Chao, Zhang, Yingying, Zhang, Hongjie, Li, Huanrong, Liu, Kai, Li, Jingjing |
| المصدر: |
Angewandte Chemie International Edition; 4/8/2024, Vol. 63 Issue 15, p1-9, 9p |
| مصطلحات موضوعية: |
SPIDER silk, SYNTHETIC fibers, RAYON, FIBERS, MODULAR design |
| مستخلص: |
Synthetic spidroin fibers have not yet attained the same level of toughness and stability as natural spider silks due to the complexity of composition and hierarchical structure. Particularly, understanding the intricate interactions between spidroin components in spider fiber is still elusive. Herein, we report modular design and preparation of spidroin‐mimetic fibers composed of a conservative C‐terminus spidroin module, two different natural β‐sheets modules, and a non‐spidroin random‐coil module. The resulting fibers exhibit a toughness of ~200 MJ/m3, reaching the highest value among the reported artificial spider silks. The interactions between two components of recombinant spidroins facilitate the intermolecular co‐assembly of β‐sheets, thereby enhancing the mechanical strength and reducing batch‐to‐batch variability in the dual‐component spidroin fibers. Additionally, the dual‐component spidroin fibers offer potential applications in implantable or even edible devices. Therefore, our work presents a generic strategy to develop high‐performance protein fibers for diverse translations in different scenarios. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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