دورية أكاديمية

Modified Glasgow Prognostic Score Predicted High-Grade Intracoronary Thrombus in Acute Anterior Myocardial Infarction.

التفاصيل البيبلوغرافية
العنوان: Modified Glasgow Prognostic Score Predicted High-Grade Intracoronary Thrombus in Acute Anterior Myocardial Infarction.
المؤلفون: Zehir, Regayip, Yılmaz, Ahmet Seyda, Çırakoğlu, Ömer Faruk, Kahraman, Fatih, Duman, Hakan
المصدر: Angiology; May2024, Vol. 75 Issue 5, p454-461, 8p
مصطلحات موضوعية: MYOCARDIAL infarction diagnosis, MYOCARDIAL infarction complications, CORONARY thrombosis, HOSPITAL care, SCIENTIFIC observation, BLOOD collection, SEVERITY of illness index, RETROSPECTIVE studies, DESCRIPTIVE statistics, ODDS ratio, COMPARATIVE studies, CONFIDENCE intervals, CORONARY angiography, BIOMARKERS, C-reactive protein, SERUM albumin
مستخلص: High-grade intracoronary thrombus (ICT) burden leads to greater myocardial injury following anterior myocardial infarction (MI). The modified Glasgow prohgnostic score (mGPS) is a novel immune-inflammatory index, calculated by using C-reactive protein (CRP) and albumin levels, was shown to have prognostic value in heart diseases. The present study investigated the role of mGPS in predicting high grade ICT in patients with acute anterior MI admitted between February 2017 and March 2020. Blood samples were obtained at admission and mGPS was calculated. The ICT burden was evaluated visually from angiographic images. Patients were divided into 2 groups according to the ICT burden as high and low. A total of 1132 patients were enrolled: a mean age 61 ± 12.4 years and 370 males (32.7%). Serum albumin was lower, whereas mGPS and CRP were higher in high grade ICT group. CRP (odds ratio (OR): 1.404 95% CI: 1.312–1.502; P <.001), albumin (OR:.486; 95% CI:.301–.782 P <.001), and mGPS (0 vs ≥ 1) (OR: 7.391; 95% CI: 3.910–13.972; P <.001) were independent predictors of high-grade ICT burden in the left anterior descending coronary artery. The mGPS is a novel predictor of high-grade ICT burden and may be useful for risk stratification in patients with acute anterior MI. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00033197
DOI:10.1177/00033197231157929