التفاصيل البيبلوغرافية
العنوان: |
A New Class of Tyrosinase Inhibitors for Skin Luminosity. |
المؤلفون: |
Hettwer, S., Gyenge, E. Besic, Schoeffel, L., Suter, B., Obermayer, B. |
المصدر: |
SOFW Journal (English version); Apr2024, Vol. 150 Issue 4, p24-28, 5p |
مصطلحات موضوعية: |
SKIN color lighteners, COSMETICS, PHENOL oxidase, RAW materials, ARTIFICIAL intelligence |
مستخلص: |
Although some skin-lightening cosmetic raw materials already exist, their effectiveness particularly on human tyrosinase has not been directly measured in every case or has not shown convincing performance in-vitro. Some active ingredients are even irritating to the skin and are restricted accordingly by some cosmetics legislations. The search for new, skin-friendlier skin-lightening raw materials has led to the development of promising candidates in recent years. Here we present a barley germ extract containing a new class of active ingredients - hordatines - with superior tyrosinase inhibition properties. The great potential of these molecules was revealed with the help of artificial intelligence by molecular docking to the tyrosinase structure. [ABSTRACT FROM AUTHOR] |
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قاعدة البيانات: |
Complementary Index |