التفاصيل البيبلوغرافية
| العنوان: |
A New Class of Tyrosinase Inhibitors for Skin Luminosity. |
| المؤلفون: |
Hettwer, S., Gyenge, E. Besic, Schoeffel, L., Suter, B., Obermayer, B. |
| المصدر: |
SOFW Journal (English version); Apr2024, Vol. 150 Issue 4, p24-28, 5p |
| مصطلحات موضوعية: |
SKIN color lighteners, COSMETICS, PHENOL oxidase, RAW materials, ARTIFICIAL intelligence |
| مستخلص: |
Although some skin-lightening cosmetic raw materials already exist, their effectiveness particularly on human tyrosinase has not been directly measured in every case or has not shown convincing performance in-vitro. Some active ingredients are even irritating to the skin and are restricted accordingly by some cosmetics legislations. The search for new, skin-friendlier skin-lightening raw materials has led to the development of promising candidates in recent years. Here we present a barley germ extract containing a new class of active ingredients - hordatines - with superior tyrosinase inhibition properties. The great potential of these molecules was revealed with the help of artificial intelligence by molecular docking to the tyrosinase structure. [ABSTRACT FROM AUTHOR] |
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Copyright of SOFW Journal (English version) is the property of Verlag fuer chemische Industrie H. Ziolkowsky GmbH and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
