التفاصيل البيبلوغرافية
| العنوان: |
The EASEMENT study: A multicentre, observational, cross‐sectional study to evaluate patient preferences, treatment satisfaction, quality of life, and healthcare resource use in patients with multiple myeloma receiving injectable‐containing or fully oral therapies |
| المؤلفون: |
Ayto, Robert, Annibali, Ombretta, Biedermann, Patricia, Roset, Montserrat, Sánchez, Emilio, Kotb, Rami |
| المصدر: |
European Journal of Haematology; Jun2024, Vol. 112 Issue 6, p889-899, 11p |
| مصطلحات موضوعية: |
PATIENT satisfaction, PATIENT preferences, MULTIPLE myeloma, PHYSICIANS' attitudes, QUALITY of life |
| مصطلحات جغرافية: |
ITALY |
| مستخلص: |
Objective: As multiple myeloma (MM) therapies advance, understanding patients', caregivers', and physicians' perspectives on, and satisfaction with, available treatment options and their impact on quality of life (QoL), is important. Methods: EASEMENT is a real‐world, observational, cross‐sectional study conducted in 19 sites within the UK, Canada, and Italy using retrospective chart reviews and surveys. Enrolled patients had clinical history available since diagnosis and had received ≥1 cycle of their current line of therapy. Primary objectives were to describe patient/caregiver QoL (EQ‐5D‐5L questionnaire), patient preference for oral/injectable therapies (single discrete‐choice question), and patient satisfaction (TSQM‐9 questionnaire). Results: Between October 2018 and March 2020, 399 patients were enrolled (n = 192 newly diagnosed multiple myeloma [NDMM], n = 206 relapsed/refractory multiple myeloma [RRMM], n = 1 missing). Among NDMM and RRMM patients, 78%/22% and 42%/58% were receiving injectables/orals, respectively. Both NDMM and RRMM patients significantly preferred orals versus injectables (p <.0001). No significant differences were reported in treatment satisfaction or QoL, but treatment convenience favoured orals over injectables with near significance (p =.053). Conclusion: MM patients perceived greater convenience and preference for orals versus injectables. Oral treatments are useful for patients who cannot or prefer not to travel to clinics, or cannot perform self‐injection within the community. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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