دورية أكاديمية

A STUDY OF ETIOLOGY, CLINICAL PROFILE AND PREDICTIVE FACTORS FOR DEVELOPMENT OF SPONTANEOUS BACTERIAL PERITONITIS AMONG PATIENTS WITH CIRRHOSIS OF LIVER IN A TERTIARY CARE HOSPITAL IN CHENNAI.

التفاصيل البيبلوغرافية
العنوان: A STUDY OF ETIOLOGY, CLINICAL PROFILE AND PREDICTIVE FACTORS FOR DEVELOPMENT OF SPONTANEOUS BACTERIAL PERITONITIS AMONG PATIENTS WITH CIRRHOSIS OF LIVER IN A TERTIARY CARE HOSPITAL IN CHENNAI.
المؤلفون: Kumar, J. Rishi, Duraisingam, Aishwarya, Kamil, Mohamed
المصدر: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2024, Vol. 15 Issue 3, p1518-1526, 9p
مصطلحات موضوعية: CIRRHOSIS of the liver, BUDD-Chiari syndrome, ETIOLOGY of diseases, PERITONITIS, TERTIARY care
مصطلحات جغرافية: CHENNAI (India)
مستخلص: Background This study was conducted to evaluate the clinical profile and predictive markers for the development of spontaneous bacterial peritonitis, as well as the frequent etiological reasons producing it in patients with decompensated liver disease. Methods In the general medicine wards of Government Stanley Hospital in Chennai, 82 patients with a history of decompensated chronic liver disease and ascites diagnosed as spontaneous bacterial peritonitis participated in this hospital-based prospective observational study. The study was conducted from June 2019 to June 2020 and was approved by the institutional ethics committee. The participants written informed consent was obtained. Results When previous SBP and outcome are compared using Pearson's chi-squared test, a statistically significant correlation is found between the two. It was statistically significant to compare total bilirubin with the outcome using the unpaired t-test. Serum albumin and the outcome by unpaired t-test comparison were statistically significant. Serum creatinine and outcome were compared using an unpaired t-test, and the results were statistically significant. According to the unpaired t-test, serum sodium and the outcome were highly statistically significant. The INR and unpaired outcome comparisons show a statistically significant difference. The unpaired t-test comparison of the ascitic fluid PMN and the outcome reveals a highly statistically significant difference. Ascitic protein and outcome are compared using an unpaired t-test, which reveals statistical significance. A statistically significant comparison was made between Child Pugh and the outcome using Pearson's chi-squared test. High statistical significance was seen when the HE grade and Pearson's chi-squared outcome were compared. Conclusion In the study population, alcoholic cirrhosis was the most common cause of cirrhosis, followed by Budd-Chiari syndrome. Abdominal distension was the most frequent clinical presentation, and it was followed by GI bleeding, fever, hepatic encephalopathy, and abdominal discomfort. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index