التفاصيل البيبلوغرافية
| العنوان: |
Genetic diversity and phylogeographic dynamics of avihepadnavirus: a comprehensive full-length genomic view. |
| المؤلفون: |
Sikandar, Muhammad, Shah, Pir Tariq, Li Xing |
| المصدر: |
Frontiers in Veterinary Science; 2024, p1-6, 6p |
| مصطلحات موضوعية: |
HEPATITIS B virus, GENETIC variation, SNOW goose, VIRAL genomes, HEPATITIS B, GENETIC recombination, CHLOROPLAST DNA, BIRDS |
| مستخلص: |
Avihepadnavirus is a genus of the Hepadnaviridae family. It primarily infects birds, including species of duck, geese, cranes, storks, and herons etc. To understand the genetic relatedness and evolutionary diversity among avihepadnavirus strains, a comprehensive analysis of the available 136 full-length viral genomes (n = 136) was conducted. The genomes were classified into two major genotypes, i.e., GI and GII. GI viruses were further classified into 8 sub-genotypes including DHBV-I (duck hepatitis B virus-I), DHBV-II (Snow goose Hepatitis B, SGHBV), DHBV-III, RGHBV (rossgoose hepatitis B virus), CHBV (crane hepatitis B virus), THBV (Tinamou hepatitis B virus), STHBV (stork hepatitis B virus), and HHBV (Heron hepatitis B virus). DHBV-I contains two sub-clades DHBV-Ia and DHBVIb. Parrot hepatitis B virus (PHBV) stains fall into GII which appeared as a separate phylogenetic branch/clade. All the subtypes of viruses in GI and GII seem to be genetically connected with viruses of DHBV-I by multiple mutational steps in phylogeographic analysis. Furthermore, 16 potential recombination events among different sub-genotypes in GI and one in GII were identified, but none of which is inter-genotypic between GI and GII. Overall, the results provide a whole picture of the genetic relatedness of avihepadnavirus strains, which may assist in the surveillance of virus spreading. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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