التفاصيل البيبلوغرافية
| العنوان: |
Phytochemical analysis, antiproliferative, antibacterial, antifungal, and antiviral activities of bitter orange (Citrus aurantium) leaf essential oil. |
| المؤلفون: |
Mejri, Houda, Aidi Wannes, Wissem, Azeiz, Sana, Hammami, Majdi, Hamdaoui, Ghaith, Dussault, Catherine, Legault, Jean, Saidani-Tounsi, Moufida |
| المصدر: |
Plant Biosystems; Jun2024, Vol. 158 Issue 3, p408-418, 11p |
| مصطلحات موضوعية: |
ESSENTIAL oils, HUMAN herpesvirus 1, CITRUS, ORANGES, CARYOPHYLLENE |
| مستخلص: |
The young and old leaves of bitter orange (Citrus aurantium) were examined for their essential oil (EO) compositions, anticancer, antimicrobial, and antiviral activities. The EO yields were 0.77% in young leaves and 0.26% in old leaves. The EO composition showed the predominance of sabinene (37.17%), E-β-ocimene (8.21%), δ-3-carene (7.71%), linalool (7.35%), and limonene (5.43%) in young leaves while of sabinene (47.47%), β-sinensal (5.71%), E-β-ocimene (4.98%), δ-3-carene (4.11%), and β-caryophyllene (4.06%) in old leaves. The EOs of both young and old leaves showed potent cytotoxic activities against human lung carcinoma (A549) and colon adenocarcinoma (DLD-1) cells with IC50 < 0.1 µg/mL. The young leaf EO had higher antibacterial activity than the old leaf EO for all bacterial strains with inhibition zones (IZ) varying from 17 to 45 and 8 to 36 mm, respectively. The EOs of both young and old leaves had strong antifungal activity against all fungal strains with IZ = 90 mm. The young leaf EO was found to be the most active in protecting cells against Herpes simplex virus type-1 (HSV-1) infection during the protection, absorption, and direct periods as compared to the untreated and treated Vero cells except the replication phase. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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