التفاصيل البيبلوغرافية
| العنوان: |
Surveillance of Antimicrobial Resistance of Escherichia coli Isolates from Intestinal Contents of Dairy and Veal Calves in the Veneto Region, Northeaster Italy. |
| المؤلفون: |
Bortolami, Laura, Barberio, Antonio, Schiavon, Eliana, Martignago, Federico, Littamè, Erica, Sturaro, Anna, Gagliazzo, Laura, De Lucia, Alessia, Ostanello, Fabio |
| المصدر: |
Animals (2076-2615); May2024, Vol. 14 Issue 10, p1429, 18p |
| مصطلحات موضوعية: |
GASTROINTESTINAL contents, DRUG resistance in microorganisms, CALVES, ESCHERICHIA coli, ANIMAL herds, DAIRY farm management, COLISTIN |
| مصطلحات جغرافية: |
VENETO (Italy), ITALY |
| مستخلص: |
Simple Summary: One key factor in the emergence of antimicrobial resistance (AMR) in microorganisms is antimicrobial usage in veterinary and human medicine. In dairy cattle, the prevalence of AMR E. coli is age-dependent, with a higher prevalence detected during the early stages of life. In veal calf fattening herds, the high degree of commingling calves from different farms of origin can lead to the rapid spread of infections within the farm. This can cause severe health issues, necessitating greater use of antimicrobial agents. Antimicrobial use has been reported to be higher in the veal calf fattening sector compared to the other production branches of livestock production. This represents an unquantified risk to human health, as antimicrobial-resistant bacteria and the genetic elements mediating resistance can potentially spread through foodborne transmission or environmental dissemination. This surveillance study was conducted, using data available from routine diagnostic activity, to: (i) determine the proportion of antimicrobial-resistant strains and AMR profiles of E. coli isolated from the intestinal contents of veal and dairy calves in the Veneto Region (Northeaster Italy); (ii) investigate potential variation in the AMR profiles of isolates between the two categories of calves and, (iii) identify potential AMR variations over the period considered (2017–2022). This surveillance study aimed to estimate the proportion of antimicrobial resistant strains and antimicrobial resistance (AMR) profiles of E. coli isolates detected from the intestinal contents of veal and dairy calves in the Veneto Region, Northeaster Italy. Additionally, we investigated the differences in AMR profiles between dairy and veal calves over the period 2017–2022. Overall 1150 E. coli isolates were tested from calves exhibiting enteric disease, with 868 from dairy and 282 from veal calves. The percentage of resistant isolates to nine antimicrobials was notably higher in veal calves compared to dairy calves, except for ampicillin. Throughout the study period, we observed a significant increase in the proportion of resistant isolates to florfenicol, gentamycin, paromomycin, tetracycline and trimethoprim/sulfamethoxazole in dairy calves, while we did not detect any significant increase in the proportion of resistant isolates among veal calves. A substantial proportion (75.9%) of the isolated E. coli exhibited multi-drug resistance (MDR). The proportion of multi-drug resistant isolates was significantly higher in veal calves (91.7%) compared to dairy calves (74.3%) all through the surveillance period (2017–2022), with no significant variation in MDR proportion among veal calves between 2017 and 2022 but a significant increase among dairy calves. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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