التفاصيل البيبلوغرافية
| العنوان: |
Gestational Diabetes Mellitus and Its Correlation in the Development of Pancreatic Cancer: A 10-Year Systematic Review. |
| المؤلفون: |
Tsokkou, Sophia, Konstantinidis, Ioannis, Georgaki, Maria-Nefeli, Kavvadas, Dimitrios, Papadopoulou, Kyriaki, Keramas, Antonios, Sioga, Antonia, Papamitsou, Theodora, Karachrysafi, Sofia |
| المصدر: |
Cancers; May2024, Vol. 16 Issue 10, p1840, 13p |
| مصطلحات موضوعية: |
RISK assessment, ADENOCARCINOMA, GESTATIONAL diabetes, PANCREATIC tumors, SYSTEMATIC reviews, MEDLINE, ONLINE information services, DISEASE risk factors, DISEASE complications |
| مستخلص: |
Simple Summary: The purpose of this systematic review was to investigate the correlation between gestational diabetes mellitus—the diabetes women experience during pregnancy—and the development of pancreatic cancer. Thus, for this research a 10-year literature review was conducted using the keywords "gestational diabetes mellitus", "pancreatic cancer" and "adenocarcinoma" in research databases such as PubMed, Scopus and ScienceDirect. After the exclusion criteria were added and the duplicates were removed, the articles were examined for their eligibility, and those suited for the study based on the degree of relevance were included. From the articles selected, the necessary data were extracted into tables, and the necessary information was summarized. Furthermore, a quality assessment was performed based on the type of study found, which revealed a high level of eligibility and related content, making the articles sufficient for us to conclude that gestational diabetes mellitus and pancreatic cancer are correlated. Purpose: Pancreatic cancer (PC) is a fatal malignancy with an aggressive course derived from the cells of pancreatic tissue. Gestational diabetes mellitus (GDM) is a state of spontaneous hyperglycemia occurring during gestation and has been suggested as a risk factor PC. Women with a history of GDM revealed a risk rate of 7.1% for the development of PC. The current systematic review aims to investigate the correlation between GDM and the degree to the prevalence of PC. Methodology: For this systematic review, the PICO model was prepared to construct and outline the exact questions of the study, a PRISMA flow diagram was prepared and quality assessment was conducted using the Newcastle Ottawa Scale (NOS) for Cohort Studies, the NIH Quality Assessment Tool-Criteria for Case Reports and the Cochrane quality assessment tool for Systematic Reviews and Meta-analysis studies. Result: A total of eight articles were retrieved from the main databases, and a table was created to summarize the information found. Even though the data found were limited, the quality assessment performed revealed that the articles were of high validity. Conclusions: It can be concluded that GDM has an association with the development of PC and can be considered as a risk factor. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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