التفاصيل البيبلوغرافية
| العنوان: |
Congenital Vascular Malformations in Children: From Historical Perspective to a Multidisciplinary Approach in the Modern Era—A Comprehensive Review. |
| المؤلفون: |
Bouwman, Frédérique C. M., Verhoeven, Bas H., Klein, Willemijn M., Schultze Kool, Leo J., de Blaauw, Ivo |
| المصدر: |
Children; May2024, Vol. 11 Issue 5, p567, 15p |
| مصطلحات موضوعية: |
ARTERIOVENOUS malformation, PATIENT safety, THERAPEUTIC embolization, CELLULAR signal transduction, GENE expression, SCLEROTHERAPY, QUALITY of life, FETAL development, GENETIC mutation, BLOOD-vessel abnormalities, CHILDREN |
| مستخلص: |
Congenital vascular malformations (CVMs) are the result of an aberrant development during embryogenesis. Although these lesions are present at birth, they are not always visible yet. Once symptomatic, patients suffer from pain, bleeding, ulcers, infections or lymphatic leakage, depending on the subtype of vessels involved. Treatment includes conservative management, surgery, sclerotherapy, embolization and pharmacological therapy. The clinical presentation varies widely and treatment can be challenging due to the rarity of the disease and potential difficulties of treatment. This review gives an overview of the historical developments in diagnosis and classification and exposes the key elements of innovations in the past decades on the identification of genetic mutations and personalized treatment. These advances in the field and a multidisciplinary approach are highly valuable in the optimization of clinical care aimed at both curing or stabilizing the CVM and pursuing physical and psychosocial wellbeing. [ABSTRACT FROM AUTHOR] |
|
Copyright of Children is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder