التفاصيل البيبلوغرافية
| العنوان: |
Photo induced eosin-Y catalyzed synthesis and molecular docking studies of 5,5-diphenylimidazolidine-2,4-dione. |
| المؤلفون: |
Garima, Km, Kumar, Rohit, Srivastava, Vishal, Singh, Praveen Pratap, Singh, Pravin Kumar |
| المصدر: |
Synthetic Communications; 2024, Vol. 54 Issue 12, p1017-1029, 13p |
| مصطلحات موضوعية: |
MOLECULAR docking, BINDING energy, CHEMICAL synthesis, BENZIL, PHOTOGRAPHS, THIOUREA |
| مستخلص: |
One-pot photo induced eosin-Y catalyzed, green approach for the synthesis of 5,5-diphenylimidazolidine-2,4-dione (Phenytoin) has been developed. The reaction proceeded smoothly, for a wide range of benzil and urea/thiourea derivatives as cheap and eco friendly reagents with high reactivity and good selectivity in DMSO as green solvent at room temperature in good to excellent yields. Biological studies such as drug-likeness and molecular docking have been conducted on the synthesized compounds, some of the compounds showed appreciable activity with least binding energy. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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