التفاصيل البيبلوغرافية
| العنوان: |
Syntheses of 7a-Substituted Pyrrolizidine Derivatives via Stereocontrolled Anionic Cyclization. |
| المؤلفون: |
Ming, Hongjun, He, Darong, Si, Shengmeng, Xu, Chao, Yuan, Yunge, Tian, Xiaoran, Hu, Zhigang, Li, Shikuo, Zhang, Hui, Huang, Fangzhi, Chen, Yue-Lei |
| المصدر: |
Synthesis; Jul2024, Vol. 56 Issue 13, p2059-2065, 7p |
| مصطلحات موضوعية: |
RING formation (Chemistry), CYCLIC compounds, KETONES, IMINOSUGARS, STEREOCHEMISTRY |
| مستخلص: |
This article discusses the synthesis of 7a-substituted pyrrolizidine derivatives through stereocontrolled anionic cyclization. The derivatives have potential therapeutic applications and the authors describe a new route for their synthesis using proline derivatives and epichlorohydrin. The compounds were successfully synthesized with controlled stereochemistry and characterized using spectroscopic techniques. The text provides detailed information on the reactions, yields, physical properties, and spectroscopic data of the compounds, making it a valuable resource for researchers studying organic chemistry and chemical synthesis. [Extracted from the article] |
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| قاعدة البيانات: |
Complementary Index |
