دورية أكاديمية

Rural-urban Differences in Long-term Mortality and Readmission Following COVID-19 Hospitalization, 2020 to 2023.

التفاصيل البيبلوغرافية
العنوان: Rural-urban Differences in Long-term Mortality and Readmission Following COVID-19 Hospitalization, 2020 to 2023.
المؤلفون: Yousufuddin, Mohammed, Mahmood, Maryam, Barkoudah, Ebrahim, Badr, Fatimazahra, Khandelwal, Kanika, Manyara, Warren, Sharma, Umesh, Abdalrhim, Ahmed D, Issa, Meltiady, Bhagra, Sumit, Murad, Mohammad H
المصدر: Open Forum Infectious Diseases; May2024, Vol. 11 Issue 5, p1-9, 9p
مصطلحات موضوعية: RURAL-urban differences, PATIENT readmissions, COVID-19, HOSPITAL care, MORTALITY
مستخلص: Background We compared long-term mortality and readmission rates after COVID-19 hospitalization based on rural-urban status and assessed the impact of COVID-19 vaccination introduction on clinical outcomes by rurality. Methods The study comprised adults hospitalized for COVID-19 at 17 hospitals in 4 US states between March 2020 and July 2022, followed until May 2023. The main analysis included all patients, whereas a sensitivity analysis focused on residents from 4 states containing 17 hospitals. Additional analyses compared the pre- and postvaccination periods. Results The main analysis involved 9325 COVID-19 hospitalized patients: 31% were from 187 rural counties in 31 states; 69% from 234 urban counties in 44 states; the mean age was 65 years (rural, 66 years; urban, 64 years); 3894 women (rural, 41%; urban, 42%); 8007 Whites (rural, 87%; urban, 83%); 1738 deaths (rural, 21%; urban, 17%); and 2729 readmissions (rural, 30%; urban, 29%). During a median follow-up of 602 days, rural residence was associated with a 22% higher all-cause mortality (log-rank, P <.001; hazard ratio, 1.22; 95% confidence interval, 1.10-1.34, P <.001), and a trend toward a higher readmission rate (log-rank, P =.038; hazard ratio, 1.06; 95% confidence interval,.98-1.15; P =.130). The results remained consistent in the sensitivity analysis and in both pre- and postvaccination time periods. Conclusions and Relevance Patients from rural counties experienced higher mortality and tended to be readmitted more frequently following COVID-19 hospitalization over the long term compared with those from urban counties, a difference that remained even after the introduction of COVID-19 vaccines. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:23288957
DOI:10.1093/ofid/ofae197