التفاصيل البيبلوغرافية
| العنوان: |
STUDY OF CLINICAL PROFILE, DIAGNOSIS AND MANAGEMENT OF PATIENTS WITH SYMPTOMATIC PULMONARY EMBOLISM. |
| المؤلفون: |
Goteti, V. Nageswara Rao, Naidu, Sujith Kumar |
| المصدر: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2024, Vol. 15 Issue 6, p411-418, 8p |
| مصطلحات موضوعية: |
PULMONARY embolism, THROMBOSIS, DIAGNOSIS, PULMONARY arterial hypertension, BLOOD circulation, ARTERIAL occlusions |
| مستخلص: |
Back ground of the study: Pulmonary thromboembolism (PTE) is an occlusion of pulmonary arterial circulation by a blood clot formed elsewhere, usually in the deep veins of the leg; less than 5% of venous thrombosis occurs in other sites. It is a major health concern with high mortality and morbidity. The aim of this Research was to study clinical profile, management and outcome of Pulmonary embolism. Methods: Prospective assessment of clinical features, radiology and outcome of patients presenting with symptomatic PE over one year period, between 01/06/2018 to 31/05/2019. PESI (pulmonary embolism severity index score), predisposing factors, symptoms, clinical feature at the time of admission, ECG features, echocardiogram, treatment received and the outcome were reviewed. Results: The study has 53 participants. The mean age was 49.15±16.08 years. The most prevalent clinical symptoms were tachycardia (79.25%) and hypotension (33.96%).The study population had a mean PESI score of 96.72 ± 31.95. The most prevalent ECG results were sinus tachycardia (79.25%) and s1q3t3 pattern (52.83%). Most patients had right atrial and right ventricular dilatation (73.58%) and 2D echo showed pulmonary arterial hypertension (73.58%).CT pulmonary angiograms showed lobar thrombus distribution in 67.92% of patients. Tenecteplase thrombolysis (69.81%), traditional heparin infusion for 3-5 days, or acitrom anticoagulation were the most common, followed by streptokinase (9.43%) and reteplase (1.89%).10 (18.87%) individuals received just anticoagulation. In this trial, most patients in the anticoagulation-only group got standard heparin for 3-5 days before acitrom (80%).The most common anticoagulants at discharge were acitrom (75.47%), rivaroxaban (13.20%), dabigatran (3.77%), apixaban (1.88%), and warfarin (1.88%). At discharge, the mean acitrom dose was 2.39 ± 0.9 mg. Most patients (96.23%) were released in stable clinical condition, with a 3.77% mortality rate. Conclusion: Pulmonary embolism is a prevalent condition that can be readily diagnosed if it is clinically suspected. Early detection and proactive treatment are crucial for a successful outcome. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
