التفاصيل البيبلوغرافية
| العنوان: |
Early-onset hepatic veno-occlusive disease after liver transplantation: an institutional experience and analysis of a literature-based cohort. |
| المؤلفون: |
Endo, Yutaka, Shinoda, Masahiro, Maehara, Junki, Hibi, Taizo, Hasegawa, Yasushi, Obara, Hideaki, Kitago, Minoru, Ojima, Hidenori, Tanabe, Minoru, Kitagawa, Yuko |
| المصدر: |
Surgery Today; Jul2024, Vol. 54 Issue 7, p670-682, 13p |
| مصطلحات موضوعية: |
HEPATIC veno-occlusive disease, LIVER transplantation, GRAFT rejection, DRUG side effects, LIVER diseases, LITERATURE reviews |
| مستخلص: |
Purpose: Hepatic veno-occlusive disease (HVOD) after liver transplantation (LT) is almost always a fatal complication. We assessed the outcomes of HVOD in a single institute and analyzed a literature-based cohort. Methods: We reviewed the medical records of recipients of LT performed between 1995 and 2020 at our institute and the literature on HVOD after LT. We then analyzed the clinical features based on a "pooled" cohort of cases identified in our institute and reported in the literature. Results: HVOD was diagnosed in 3 of 331 LT recipients, all of whom died in hospital, on days 164, 12, and 13, respectively. Our comprehensive review of the literature, as well as our cases, identified eight cases of HVOD that developed within 14 days after LT (early-onset type). Early-onset HVOD had a significantly worse prognosis than HVOD that developed beyond 2 weeks after LT (non-early-onset type), which was identified in 22 cases (25.0% vs. 86.1% of the 3-month graft survival rate). The most common causes of early-onset and non-early-onset types were acute cellular rejection (50%) and drug-induced disease (50%), respectively. Conclusion: Early-onset HVOD developing within 14 days after LT has a poor prognosis. [ABSTRACT FROM AUTHOR] |
|
Copyright of Surgery Today is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Find this article in full text from Springer Verlag. 
Full Text Finder