التفاصيل البيبلوغرافية
| العنوان: |
Pseudo Elevation of TSH and ACTH Caused by Heterophilic Antibodies: a Case Report and Literature Review. |
| المؤلفون: |
Hong-Gang Sun, Xiu-Ping Xu, Li-Qin He |
| المصدر: |
Clinical Laboratory; 2024, Vol. 70 Issue 6, p1228-1231, 4p |
| مصطلحات موضوعية: |
LITERATURE reviews, ADRENOCORTICOTROPIC hormone, THYROTROPIN receptors, THYROTROPIN, IMMUNOGLOBULINS, ADRENAL diseases |
| الشركة/الكيان: |
SIEMENS AG |
| مستخلص: |
Background: TSH and ACTH are crucial hormones for diagnosing thyroid and adrenal diseases, and incorrect test reports can cause significant harm to patients. Methods: The TSH and ACTH levels on the testing system of our laboratory were measured using "sandwich" assays. The patient had heterophilic antibodies in their body, causing a false increase in TSH and ACTH levels. Results: TSH on the Abbott platform was 59.7 µIU/mL and on the Roche platform it was 4.33 µIU/mL. After pretreatment with HBR it was 3.95 µIU/mL; ACTH on the SIEMENS platform was 263.5 pg/mL, on the Abbott platform it was 47.6 pg/mL. After pre-treatment with HBR it was 36.5 pg/mL. Conclusions: The patient's serum contains heterophilic antibodies, which interfere with the TSH and ACTH tested by this method. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
