التفاصيل البيبلوغرافية
| العنوان: |
Measurement of Trace Elements (Zinc, Copper, Magnesium, and Iron) in the Saliva of Horses: Validation Data and Changes in Equine Gastric Ulcer Syndrome (EGUS). |
| المؤلفون: |
Muñoz-Prieto, Alberto, Cerón, José Joaquín, Tecles, Fernando, Cuervo, María Martín, Contreras-Aguilar, Maria Dolores, Ayala, Ignacio, Oudada-Guillén, Adrián, Pardo-Marín, Luis, Hansen, Sanni |
| المصدر: |
Animals (2076-2615); Jun2024, Vol. 14 Issue 12, p1724, 12p |
| مصطلحات موضوعية: |
STOMACH ulcers, TRACE elements, IRON, HORSES, MAGNESIUM, SALIVA, GASTRIC diseases |
| مستخلص: |
Simple Summary: This study aimed to assess the potential of spectrophotometric assays to measure trace elements (Zinc, Copper, Magnesium, and Iron) in horse saliva and their possible changes in Equine Gastric Ulcer Syndrome (EGUS). EGUS is prevalent in horses, influenced by intensive management conditions, and encompasses equine squamous gastric disease (ESGD) and equine glandular gastric disease (EGGD). Validated spectrophotometric assays were used to measure these elements in horses with ESGD, EGGD, both, and healthy horses. Results showed significantly lower Zinc and Magnesium levels in horses with EGGD, while Iron concentrations were lower in ESGD and EGGD cases. These findings suggest potential biomarkers for EGUS, shedding light on its pathophysiology and aiding in diagnosis and management strategies for improved equine health. The objective of this study was to evaluate the possible use of spectrophotometric assays for the measurement of trace elements, including Zinc (Zn), Copper (Cu), Magnesium (Mg), and iron (Fe) in the saliva of horses and study their possible changes in equine gastric ulcer syndrome (EGUS). EGUS is a highly prevalent disease, with a current high incidence due to the increase in intensive management conditions. There are two EGUS diseases: equine squamous gastric disease (ESGD) and equine glandular gastric disease (EGGD), which can appear individually or together. For this purpose, automated spectrophotometric assays for measuring these analytes in horse saliva were analytically validated. Then, these analytes were measured in the saliva of horses with only ESGD, only EGGD, both ESGD and EGGD and a group of healthy horses. The methods used to measure the analytes were precise and accurate. Horses diagnosed with EGGD presented significantly lower levels of Zn and Mg. Fe concentrations were significantly lower in the saliva of horses with ESGD and EGGD. Overall, these results indicate that there are changes in trace elements in saliva in EGUS that could reflect the physiopathological mechanisms involved in this process and open the possibility of using trace elements as biomarkers of this syndrome. [ABSTRACT FROM AUTHOR] |
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