دورية أكاديمية

Pregnancy‐associated atypical hemolytic uremic syndrome. Case report.

التفاصيل البيبلوغرافية
العنوان: Pregnancy‐associated atypical hemolytic uremic syndrome. Case report.
المؤلفون: Barrera‐Hoffmann, Christopher, Mariaca‐Ortíz, Yadira, Ruiz‐Villa, Josué Giovani, Cuevas‐Cruz, Lesllie Eugenia, López‐Mendoza, María del Rosario, Briones‐Garduño, Jesús Carlos
المصدر: Journal of Obstetrics & Gynaecology Research; Jul2024, Vol. 50 Issue 7, p1268-1272, 5p
مصطلحات موضوعية: HEMOLYTIC-uremic syndrome diagnosis, DIAGNOSIS of blood diseases, BLOOD disease treatment, HEMOLYTIC-uremic syndrome treatment, PLATELET count, CREATININE, RARE diseases, ASPARTATE aminotransferase, PLASMAPHERESIS, HEMODIALYSIS, LACTATE dehydrogenase, MEAN platelet volume, THROMBOCYTOPENIA, NEUROLOGICAL disorders, SEPTIC shock, MONOCLONAL antibodies, GESTATIONAL age, ALANINE aminotransferase, URINALYSIS, PREGNANCY complications, PLASMA exchange (Therapeutics), DEXAMETHASONE, PREGNANCY
مستخلص: Pregnancy‐associated atypical hemolytic uremic syndrome (P‐aHUS) is a rare disease. There are only few reports in the literature, and most are in the puerperium period. It is a thrombotic microangiopathy (TMA) characterized for microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. We report the case of a pregnant patient at 26.3 gestation weeks, who developed clinical features of TMA, neurological alterations, and septic shock; then after fetus and placental delivery, no clinical improvement was observed; a diagnostic protocol was performed due to suspicion of P‐aHUS, showing improvement after the plasma exchange sessions and eculizumab. We present here a brief review of the case since it is an entity that needs to be suspected during pregnancy when TMA features and requires an immediate diagnosis to provide timely treatment. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:13418076
DOI:10.1111/jog.15958