التفاصيل البيبلوغرافية
| العنوان: |
The synthesis of oligomers containing alternating C-glycosyl α-amino acids and proteinogenic α-amino acids. |
| المؤلفون: |
Colić, Ivana, Bogović, Barbara, Jerić, Ivanka |
| المصدر: |
New Journal of Chemistry; 7/28/2024, Vol. 48 Issue 28, p12584-12590, 7p |
| مصطلحات موضوعية: |
OLIGOMERIZATION, ACIDS, OLIGOMERS, GALACTOMANNANS, AMINO acids |
| مستخلص: |
C-Glycosyl amino acids are a group of C-glycosides in which a carbohydrate molecule is attached to the side chain or backbone of the amino acid via a C–C bond. Despite the numerous methods that have been developed for their synthesis, the C-glycosyl α-amino acids and their oligomers are relatively unexplored. In this work, we presented a protocol for the synthesis of oligomers containing alternating C-glycosyl α-amino acids and proteinogenic α-amino acids. The methodology is based on the modification of α-acyloxyamides obtained from the Passerini reaction using α- D -galactopyranose- and α- L -sorbofuranose-derived aldehydes as C-glycosyl donors. The protocol enabled the synthesis of homo- and heterochiral tetramers, and homo- and heterovalent tetramers in very good yields. [ABSTRACT FROM AUTHOR] |
|
Copyright of New Journal of Chemistry is the property of Royal Society of Chemistry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
