دورية أكاديمية

Exploring the biological potential of Cruciata taurica (Pall. ex Willd.) Ehrend.: Evaluating antibacterial, antioxidant, antidiabetic, and cytotoxic properties.

التفاصيل البيبلوغرافية
العنوان: Exploring the biological potential of Cruciata taurica (Pall. ex Willd.) Ehrend.: Evaluating antibacterial, antioxidant, antidiabetic, and cytotoxic properties.
المؤلفون: KHALIL-MOGHADDAM, SHIVA, MOGHIMI, ROYA, EFFERTH, THOMAS, MOUSAVIAN, SAJEDEH
المصدر: Trends in Phytochemical Research (TPR); Summer2024, Vol. 8 Issue 2, p131-140, 10p
مصطلحات موضوعية: ANTIOXIDANTS, HYPOGLYCEMIC agents, PLANT extracts, ANTIBACTERIAL agents, MULTIDRUG resistance
مستخلص: This study focused on the biological properties of Cruciata taurica, a plant found in the Irano-Turanian region, which has not been extensively studied in terms of its phytochemical and biological activities. The methanolic extract of the plant was obtained and its cytotoxic, antibacterial, antidiabetic, and antioxidant properties were investigated. The antibacterial activity of the fractions was evaluated using broth microdilution method, while the antioxidant properties were assessed through the DPPH assay and the cytotoxic properties were determined using the RRA assay. This study revealed that the residual aqueous fraction exhibited the highest extraction yield and the most potent antioxidant activity. The EtOAc fraction showed strong antibacterial activity against certain bacteria, while the n-hexane fraction exhibited greater antidiabetic effects. Additionally, the EtOAc fraction was found to be the most cytotoxic. Overall, the study suggested that C. taurica has potential therapeutic applications due to its various biological properties. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index