التفاصيل البيبلوغرافية
| العنوان: |
Remineralization effect of NaF, NaF with TCP, NaF with CPP‐ACP and NaF with CXP varnishes on newly erupted first permanent molars: A randomized controlled trial. |
| المؤلفون: |
Erkmen Almaz, Merve, Ulusoy, Nur Burcu, Akbay Oba, Aylin, Dokumacı, Aysun |
| المصدر: |
International Journal of Dental Hygiene; Aug2024, Vol. 22 Issue 3, p703-710, 8p |
| مصطلحات موضوعية: |
CAVITY prevention, MOLARS, XYLITOL, DATA analysis, LASERS, PERMANENT dentition, FLUORIDE varnishes, CASEINS, PHOSPHATES, STATISTICAL sampling, BLIND experiment, TREATMENT effectiveness, RANDOMIZED controlled trials, MANN Whitney U Test, DESCRIPTIVE statistics, CALCIUM, REMINERALIZATION (Teeth), STATISTICS, SODIUM compounds, COMPARATIVE studies, DATA analysis software, PHARMACODYNAMICS |
| مصطلحات جغرافية: |
TURKEY |
| مستخلص: |
Introduction: The aim of this study was to evaluate the remineralization effect of NaF, NaF with TCP, NaF with CPP‐ACP and NaF with CXP varnishes on newly erupted first permanent molars using laser fluorescence (LF) method. The study was a randomized, double‐blind, controlled trial with four parallel groups. Methods: The study was carried out in 48 high caries‐risk children (DMFS >8), aged 6–7 years with newly erupted permanent first molars (initial lesion with 13 < LF value<30). A total of 140 teeth were divided randomly into four groups (n = 35): G1.Duraphat Varnish containing 5% NaF, G2. Clinpro™ White Varnish containing 5% NaF with TCP, G3.Embrace™ Varnish containing 5% NaF with CXP, G4. MI Varnish containing 5% NaF with CPP‐ACP. All dental treatments of the patients were completed before the varnish application. The varnishes were applied to the targeted teeth at baseline, 1 and 3 months. Patients were called for follow‐up appointments at 1, 3 and 6 months, and LF scanning was used to monitor mineralization changes. Data were analysed statistically by Wilcoxon signed‐rank and Mann–Whitney U‐tests. Results: In total, 40 children (122 teeth) completed the trial. At the end of 6 months, the amount of reduction in LF values (indicating remineralization) are as follows: NaF with CXP(6.87 ± 4.32) < NaF with TCP(7.36 ± 7.05) < NaF(7.40 ± 7.03) < NaF with CPP‐ACP(8.33 ± 4.90). All of the varnishes resulted in significant decrease in LF measurements and there was no significant difference between control (NaF alone) group and other groups. Only MI varnish had a significantly greater remineralization effect than Embrace™ Varnish (p < 0.05). Conclusion: As a non‐invasive approach, CPP‐ACP, TCP and CXP containing NaF varnishes have the potential to remineralize initial caries lesions on permanent first molars in high caries‐risk children. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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