دورية أكاديمية

Development of Configurationally Labile Biaryl Reagents for Atropisomer Synthesis.

التفاصيل البيبلوغرافية
العنوان: Development of Configurationally Labile Biaryl Reagents for Atropisomer Synthesis.
المؤلفون: Wu, Changhui, Jin, Yang, Zhang, Xiaoyuan, Gao, Ruiqi, Dou, Xiaowei
المصدر: European Journal of Organic Chemistry; 7/22/2024, Vol. 27 Issue 28, p1-17, 17p
مصطلحات موضوعية: DERACEMIZATION, NATURAL products, ATROPISOMERS, ASYMMETRIC synthesis
مستخلص: Axially chiral biaryl scaffolds are important in pharmaceuticals, natural products, and asymmetric synthesis. Atroposelective ring‐opening of configurationally labile biaryl reagents via dynamic kinetic asymmetric transformation provides a valuable approach to access axially chiral biaryl atropisomers. This review summarizes seminal contributions and recent advancements on this topic based on the use of different types of configurationally labile biaryl reagents. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:1434193X
DOI:10.1002/ejoc.202400402