التفاصيل البيبلوغرافية
| العنوان: |
Sex Differences in Fractional Flow Reserve Utilization. |
| المؤلفون: |
Bujak, Marta, Malinowski, Krzysztof, Siudak, Zbigniew, Ćmiel, Anna, Lesiak, Maciej, Bartuś, Stanisław, Legutko, Jacek, Wańha, Wojciech, Witkowski, Adam, Dudek, Dariusz, Gąsior, Mariusz, Gil, Robert, Protasiewicz, Marcin, Kubica, Jacek, Godek, Piotr, Wojakowski, Wojciech, Gąsior, Paweł |
| المصدر: |
Journal of Clinical Medicine; Jul2024, Vol. 13 Issue 14, p4028, 11p |
| مصطلحات موضوعية: |
PERCUTANEOUS coronary intervention, ACUTE coronary syndrome, LITERATURE reviews, LOGISTIC regression analysis, DELAYED diagnosis, MYOCARDIAL infarction |
| مستخلص: |
Background: The literature review shows that female patients are more frequently underdiagnosed or suffer from delayed diagnosis. Recognition of sex-related differences is crucial for implementing strategies to improve cardiovascular outcomes. We aimed to assess sex-related disparities in the frequency of fractional flow reserve (FFR)-guided procedures in patients who underwent angiography and/or percutaneous coronary intervention (PCI). Methods: We have derived the data from the national registry of percutaneous coronary interventions and retrospectively analyzed the data of more than 1.4 million angiography and/or PCI procedures [1,454,121 patients (62.54% men and 37.46% women)] between 2014 and 2022. The logistic regression analysis was conducted to explore whether female sex was associated with FFR utilization. Results: The FFR was performed in 61,305 (4.22%) patients and more frequently in men than women (4.15% vs. 3.45%, p < 0.001). FFR was more frequently assessed in females with acute coronary syndrome than males (27.75% vs. 26.08%, p < 0.001); however, women with chronic coronary syndrome had FFR performed less often than men (72.25% vs. 73.92%, p < 0.001). Females with FFR-guided procedures were older than men (69.07 (±8.87) vs. 65.45 (±9.38) p < 0.001); however. less often had a history of myocardial infarction (MI) (24.79% vs. 36.73%, p < 0.001), CABG (1.62% vs. 2.55%, p < 0.005) or PCI (36.6% vs. 24.79%, p < 0.001) compared to men. Crude comparison has shown that male sex was associated with a higher frequency of FFR assessment (OR = 1.2152–1.2361, p < 0.005). Conclusions: Despite a substantial rise in FFR utilization, adoption in women remains lower than in men. Female sex was found to be an independent negative predictor of FFR use. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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