دورية أكاديمية

Incidence and risk factors of myelosuppression of linezolid in patients with drugresistant tuberculosis: A scoping review.

التفاصيل البيبلوغرافية
العنوان: Incidence and risk factors of myelosuppression of linezolid in patients with drugresistant tuberculosis: A scoping review.
المؤلفون: Putra, Oki Nugraha, Purnamasari, Telly
المصدر: One Health Bulletin; Mar2024, Vol. 4 Issue 1, p1-8, 8p
مصطلحات موضوعية: LEUKOCYTE count, NUCLEOSIDE reverse transcriptase inhibitors, SOFT tissue infections, DRUG side effects, MEDICAL personnel, MULTIDRUG-resistant tuberculosis
مستخلص: This document summarizes a scoping review on the use of linezolid in the treatment of drug-resistant tuberculosis (DR-TB). The review found that myelosuppression, particularly anemia, was a common side effect of linezolid treatment in DR-TB patients. Risk factors for myelosuppression included HIV co-infection, age, and high exposure to linezolid. Regular monitoring of hematologic parameters is recommended during linezolid treatment, especially in patients with these risk factors. The document also provides insights into dosing strategies, pharmacokinetics, and the importance of considering factors such as age and renal function when using linezolid in TB treatment. [Extracted from the article]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:27730344
DOI:10.4103/ohbl.ohbl_43_23