التفاصيل البيبلوغرافية
| العنوان: |
Reversal of Intestinal Failure With Teduglutide in PERCC1 -Associated Enteropathy: A Case Report. |
| المؤلفون: |
Stenke, Emily, Dunne, Cara, Bryce-Smyth, Anthea, Hurley, Michelle, Pode-Shakked, Ben, Anikster, Yair, Tan, Tricia, Kowalka, Anna, Bech, Paul, Bourke, Billy |
| المصدر: |
Annals of Internal Medicine; Aug2024, Vol. 177 Issue 8, p1141-1144, 6p |
| مصطلحات موضوعية: |
HORMONE therapy, LIQUID chromatography-mass spectrometry, VASOACTIVE intestinal peptide, SUBCUTANEOUS injections, ENZYME-linked immunosorbent assay, COCAINE-induced disorders, SHORT bowel syndrome |
| مستخلص: |
This article discusses a case report of a 14-year-old male with PERCC1-associated enteropathy, a rare disorder characterized by severe diarrhea and intestinal failure. The patient had low levels of enteroendocrine hormones, including glucagon-like peptide-2 (GLP-2), which plays a crucial role in intestinal function. The researchers hypothesized that GLP-2 deficiency could be treated with teduglutide, a synthetic analog of GLP-2. After starting teduglutide therapy, the patient experienced significant improvements in weight, stool frequency, and calorie intake, leading to the discontinuation of parenteral nutrition. This case suggests that teduglutide may be an effective treatment for PERCC1-associated enteropathy and other conditions characterized by enteroendocrine dysfunction. [Extracted from the article] |
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| قاعدة البيانات: |
Complementary Index |
