التفاصيل البيبلوغرافية
| العنوان: |
Prevalence, clinical features, and survival outcome trends of 627 patients with primary cutaneous lymphoma over 29 years: a retrospective review from single tertiary center in Korea. |
| المؤلفون: |
Moon, Ik Jun, Won, Chong Hyun, Chang, Sung Eun, Park, Chan-Sik, Yoon, Dok-Hyun, Song, Si Yeol, Lee, Mi Woo, Lee, Woo Jin |
| المصدر: |
Scientific Reports; 8/29/2024, Vol. 14 Issue 1, p1-9, 9p |
| مصطلحات موضوعية: |
SURVIVAL rate, CUTANEOUS T-cell lymphoma, T-cell lymphoma, MUCOSA-associated lymphoid tissue lymphoma, MYCOSIS fungoides, B cells |
| مستخلص: |
The relative frequency of primary cutaneous lymphoma (PCL) subtypes shows wide variation across different geographical regions. This retrospective study was conducted in a tertiary referral center located in Korea to describe the relative frequency, demographics, survival outcomes, and temporal trend in PCL. A total of 627 PCL cases diagnosed between January 1994 and December 2022 were included. The majority of PCL cases (87.2%) were of T-/NK-cell lineage (CTCL), while the remaining cases (12.8%) were B-cell lineage lymphomas (CBCL). The prevalence of mycosis fungoides (MF) in CTCL increased significantly over time, while other CTCL subtypes, including primary cutaneous extranodal NK/T-cell lymphoma and subcutaneous panniculitis-like T-cell lymphoma (SPTCL), decreased in frequency. Notably, the prevalence of CD4-positive small/medium T-cell lymphoproliferative disorder showed a substantial increase over time. Primary cutaneous marginal zone lymphoma was consistently the commonest CBCL subtype. Survival analysis demonstrated that CTCL had a more favorable 5-year overall survival (OS) than CBCL. OS rate of MF, SPTCL, and primary cutaneous peripheral T-cell lymphoma, NOS improved significantly over time. This study provides comprehensive insights into the dynamic change in the relative frequency and overall survival of PCL subtypes over time. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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