التفاصيل البيبلوغرافية
| العنوان: |
Radiosurgery in Grade II and III Meningiomas: A Systematic Review and Meta-Analysis. |
| المؤلفون: |
Jahanbakhshi, Amin, Najafi, Masoumeh, Gomar, Marzieh, Ciammella, Patrizia, Ruggieri, Maria Paola, Iotti, Cinzia, Finocchi Ghersi, Sebastiano, Serre, Anne-Agathe, Bardoscia, Lilia, Sardaro, Angela, Boisbouvier, Sophie, Roukoz, Camille, Cozzi, Salvatore |
| المصدر: |
Journal of Personalized Medicine; Aug2024, Vol. 14 Issue 8, p802, 15p |
| مستخلص: |
Background: Meningiomas are the most prevalent benign intracranial tumors. When they are of the invasive subtypes, i.e., grades II and III, they can recur rapidly and present a real challenge for physicians. This study is focused on the use of stereotactic radiosurgery to manage high-grade meningiomas. Method: Medline via PubMed was searched from inception to December 2022 to retrieve studies on stereotactic radiation therapy for patients with grade II-III meningiomas. This study was conducted under PRISMA guidelines. Result: A total of 29 articles involving 1446 patients with grade II-III meningiomas treated with stereotactic radiation therapy were included in the present study. Of these studies, 11 were conducted exclusively on patients with atypical meningiomas (grade II), 1 targeted anaplastic meningiomas (grade III), and 17 articles were carried out on both grade II and III meningiomas. The pooled 1, 2, 3, 5, and 10-year overall survival (OS) of grade II meningiomas was 0.96 [p < 0.01], 0.89 [p = 0.01], 0.90 [p = 0.09], 0.81 [p < 0.01], and 0.66 [p = 0.55], respectively. The pooled 2, 5, and 10-year OS of grade III meningiomas was 0.64 [p = 0.01], 0.41 [p = 0.01], and 0.19 [p < 0.01], respectively. Conclusions: Although long-term prospective studies are still required, the outcomes of stereotactic radiation therapy appear promising regarding overall outcome and progression-free survival. [ABSTRACT FROM AUTHOR] |
|
Copyright of Journal of Personalized Medicine is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder