دورية أكاديمية

Comparative analysis of body composition using torso CT from PET/CT with bioelectrical impedance and muscle strength in healthy adults.

التفاصيل البيبلوغرافية
العنوان: Comparative analysis of body composition using torso CT from PET/CT with bioelectrical impedance and muscle strength in healthy adults.
المؤلفون: Lee, Dong Yun, Oh, Jungsu S., Kim, Jeong Won, Kim, Jae Seung, Oh, Minyoung, Kim, Yong-il, Ko, Duk Han, Bae, Sung-Jin, Kim, Hong-Kyu, Ryu, Jin-Sook
المصدر: Scientific Reports; 9/16/2024, Vol. 14 Issue 1, p1-13, 13p
مصطلحات موضوعية: POSITRON emission tomography computed tomography, MUSCLE strength testing, BIOELECTRIC impedance, KOREANS, MUSCLE strength
مستخلص: The role of torso computed tomography (CT) in evaluating body composition has been unexplored. This study assessed the potential of low-dose torso CT from positron emission tomography (PET)/CT for analyzing body composition and its relation to muscle strength. We retrospectively recruited 384 healthy Korean adults (231 men, 153 women) who underwent torso 18F-FDG PET/CT, bioelectrical impedance analysis (BIA), and muscle strength tests (handgrip strength [HGS] and knee extension strength [KES]). CT images were segmented into three compartments: torso volumetric, abdominal volumetric, and abdominal areal. Muscle amounts from each compartment were indexed to height (m2). BIA and HGS served as reference standards, with correlation coefficients (r) calculated. Torso muscle volumetric index (TorsoMVI) had the strongest correlations with BIA-derived values (r = 0.80 for men; r = 0.73 for women), surpassing those from the abdominal compartments. TorsoMVI was also correlated significantly with HGS (r = 0.39, p < 0.01) and differentiated between normal and possible sarcopenia in men (n = 225, 5960 ± 785 cm3/m2 vs. n = 6, 5210 ± 487 cm3/m2, p = 0.02). In women, KES correlated more strongly with muscle parameters than HGS. Despite gender-specific variations, torso CT-derived parameters show promise for evaluating body composition and sarcopenia. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:20452322
DOI:10.1038/s41598-024-71878-2