دورية أكاديمية

Contrast-enhanced wideband harmonic imaging ultrasound (SonoVue®): A new technique for quantifying bowel wall vascularity in Crohn's disease.

التفاصيل البيبلوغرافية
العنوان: Contrast-enhanced wideband harmonic imaging ultrasound (SonoVue®): A new technique for quantifying bowel wall vascularity in Crohn's disease.
المؤلفون: Kratzer, Wolfgang, Schmidt, Stefan A>, Mittrach, Christoph, Haenle, Mark M., Mason, Richard A., Von Tirpitz, Christian, Pauls, Sandra
المصدر: Scandinavian Journal of Gastroenterology; Aug2005, Vol. 40 Issue 8, p985-991, 7p, 1 Chart
مصطلحات موضوعية: ULTRASONIC imaging, MEDICAL imaging systems, CROHN'S disease, ENTERITIS, ILEUM diseases, INFLAMMATORY bowel diseases
مستخلص: Objective. To assess the possibility of quantitative determination of bowel wall vascularity using contrast-enhanced (SonoVue®) wideband harmonic imaging ultrasound and the HDI-Lab software in patients with Crohn's disease. Material and methods. Twenty-one patients (13 F, 8 M, average age 33.8 ± 12.7 years, range 21 60 years) with histologically confirmed Crohn's disease and bowel wall thickness ⩾5 mm were recruited for the study. All ultrasound examinations were performed using a Philips HDI 5000 scanner. Bowel wall vascularity was determined at the site of maximum bowel wall thickness at baseline and at 30, 60, 90 and 120 s following application of the contrast enhancer SonoVue (1.2 ml) using the HDI-Lab software. Results. The mean length of bowel segments exhibiting increased wall thickness was 122.3 mm (range: 23 350 ± 74.7 mm), with a mean wall thickness of 7.6±1.2 mm. Onset of echo enhancement secondary to contrast medium application was observed after an average 13.4 s (range 7-19 ± 4.2 s). Echo intensity corresponding to maximum vascularity was measured 30 s after application of contrast medium. Maximum average contrast medium uptake was 217.5% (range 118-466 ± 100.1%). Conclusions. It is possible to quantify bowel wall vascularity accurately in patients with Crohn's disease using contrast-enhanced pulse inversion ultrasound (low-MI). [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00365521
DOI:10.1080/00365520510015818