دورية أكاديمية

Use of a new alginate film test to study the bactericidal efficacy of the high-level disinfectant ortho-phthalaldehyde.

التفاصيل البيبلوغرافية
العنوان: Use of a new alginate film test to study the bactericidal efficacy of the high-level disinfectant ortho-phthalaldehyde.
المؤلفون: J. C. N. Shackelford, G. W. Hanlon, J.-Y. Maillard
المصدر: Journal of Antimicrobial Chemotherapy (JAC); Feb2006, Vol. 57 Issue 2, p335-338, 4p
مستخلص: Objectives: To evaluate the merit of a new alginate efficacy film test to determine the bactericidal activity of the high-level disinfectant ortho-phthalaldehyde (OPA).Methods: The efficacy of OPA was investigated using a new sodium alginate surface film test against Mycobacterium chelonae NCIMB 1474 and Epping, and Pseudomonas aeruginosa NCIMB 10421 under different test conditions.Results: OPA was highly bactericidal against P. aeruginosa but its mycobactericidal efficacy was seriously reduced and produced ≥5 log reductions only at a concentration of 0.5% (w/v) within 30–60 min without organic load.Conclusions: The sodium alginate film efficacy was reproducible between repeats. Inactivation results depended upon the concentration of OPA, contact time, the presence of an organic load and the bacterial genera. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:03057453
DOI:10.1093/jac/dki432