التفاصيل البيبلوغرافية
| العنوان: |
Body size, weight change, fat distribution and breast cancer risk in Hispanic and non-Hispanic white women. |
| المؤلفون: |
Martha Slattery, Carol Sweeney, Sandra Edwards, Jennifer Herrick, Kathy Baumgartner, Roger Wolff, Maureen Murtaugh, Richard Baumgartner, Anna Giuliano, Tim Byers |
| المصدر: |
Breast Cancer Research & Treatment; Mar2007, Vol. 102 Issue 1, p85-101, 17p |
| مصطلحات موضوعية: |
BREAST cancer, DISEASES in women, BODY weight |
| مصطلحات جغرافية: |
SOUTHWESTERN United States |
| مستخلص: |
AbstractIntroduction??The incidence of breast cancer varies among women living in the Southwestern part of the US. We evaluate how body size influences breast cancer risk among these women.Methods??Cases (n?=? 2,325) diagnosed with breast cancer between October 1, 1999 and May 2004 residing in Arizona, Colorado, New Mexico, or Utah were matched to controls (n?=?2,525). Participants were interviewed; height, weight, waist, and hip circumference were measured at the time of interview; blood was drawn.Results??A large body mass index (BMI) at age 15 was inversely associated with pre-menopausal breast cancer risk in both non-Hispanic white (NHW) and Hispanic women (Odds ratio, ORs 0.68 95% CI 0.44, 1.04, and 0.65 95% CI 0.39, 1.08, respectively); BMI at age 15 also had an impact on subsequent breast cancer associated with obesity after menopause. Among post-menopausal women, recent exposure to hormones was an important modifier of risk associated with body size. Among women not recently exposed to hormones risk associated with obesity was 1.61 (95% CI 1.05, 2.45) for NHW women; gaining ?25?kg between 15 and age 50 was inversely associated with breast cancer among Hispanic women (OR 0.51, 95% CI 0.23, 1.14). A large weight gain and a large waist-to-hip ratio (WHR) was associated with an increased odds of having an estrogen receptor negative tumor among NHW only (OR 1.81, 95% CI 1.07, 3.08, and 2.04 95% CI 1.20,3.50).Conclusions??These findings suggest that the metabolic consequences of obesity on breast cancer risk differ between NHW and Hispanic women living in the Southwest. [ABSTRACT FROM AUTHOR] |
|
Copyright of Breast Cancer Research & Treatment is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Find this article in full text from Springer Verlag. 
Full Text Finder