دورية أكاديمية

Describing the structure and assembly of protein filaments by EPR spectroscopy of spin-labeled side chains.

التفاصيل البيبلوغرافية
العنوان: Describing the structure and assembly of protein filaments by EPR spectroscopy of spin-labeled side chains.
المؤلفون: Madhu S. Budamagunta, John Hess, Paul Fitzgerald, John Voss
المصدر: Cell Biochemistry & Biophysics; May2007, Vol. 48 Issue 1, p45-53, 9p
مستخلص: In this review we summarize our approach to the study of Intermediate Filament (IF) structure and assembly by electron paramagnetic resonance (EPR) spectroscopy of site-directed spin labels. Using vimentin, a homopolymeric type III IF protein, we demonstrate that this approach serves as a general paradigm for studying protein filament structure and assembly. These strategies will be useful in exploring the structure and assembly properties of other filamentous or aggregation-prone systems. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:10859195
DOI:10.1007/s12013-007-0035-4