التفاصيل البيبلوغرافية
| العنوان: |
Cerivastatin, a New Potent Synthetic HMG Co-A Reductase Inhibitor: Effect of 0.2 mg Daily in Subjects With Primary Hypercholesterolemia. |
| المؤلفون: |
Stein, E., Sprecher, D., Allenby, K. S., Tosiello, R. L., Whalen, E., Ripa, S. R. |
| المصدر: |
Journal of Cardiovascular Pharmacology & Therapeutics; Mar1997, Vol. 2 Issue 1, p7-16, 11p |
| مصطلحات موضوعية: |
STATINS (Cardiovascular agents), DRUG efficacy, PHARMACODYNAMICS, HYPERCHOLESTEREMIA, DRUG administration, HIGH density lipoproteins |
| مستخلص: |
This study evaluates the efficacy and safety of cerivastatin, a hydroxymethyl-coenzyme A (HMG-CoA) reductase inhibitor, in treating patients with hypercholesterolemia. The researchers evaluated patients with a history of primary hypercholesterolemia uncontrolled with dietary intervention. This study found that cerivastatin, when administered at 0.2 mg once a day in the evenings, was significantly more effective than placebo in reducing low-density lipoprotein cholesterol and raising high-density lipoprotein cholesterol. |
| قاعدة البيانات: |
Complementary Index |
