التفاصيل البيبلوغرافية
| العنوان: |
Effect of Tamsulosin in Preventing Ureteral Stent-Related Morbidity A Prospective Study. |
| المؤلفون: |
Rocco Damiano, Riccardo Autorino, Marco De Sio, Alessandro Giacobbe, Italo Michele Palumbo, Massimo D'Armiento |
| المصدر: |
Journal of Endourology; Apr2008, Vol. 22 Issue 4, p651-656, 6p |
| مصطلحات موضوعية: |
URETERIC obstruction, SURGICAL stents, LONGITUDINAL method, QUALITY of life |
| مستخلص: |
Purpose We conducted a randomized study to evaluate the effect of tamsulosin in improving symptoms and quality of life (QoL) in patients with indwelling double-pigtail ureteral stents, using both generic and specific questionnaires.Materials and Methods We prospectively enrolled 75 patients (29 men, 46 women; mean age, 42.3 years), who underwent ureteral stent positioning and were assigned to one of two study groups. In group A (n 38), patients were discharged with a prescription for tamsulosin, 0.4 mg once daily. In group B (n 37), patients received no α1-blocker (control group).Results One week after stent placement (visit week 1 [W1]), analysis of the ureteral stent symptoms questionnaire showed a significant worsening of urinary symptoms (13.1 v26.4, P 0.008) and pain (4.1 v21.6, P 0.002) in patients not receiving tamsulosin. There was also a significant difference in the mean visual analog score (VAS) of health scale between the two groups (P< 0.001) compared with the result obtained at the W4 evaluation (visit). The proportion of patients reporting level 2 or 3 for the paindiscomfort domain in the QoL questionnaire from W4 to W1 varied between the two groups in a highly statistically significant manner (P 0.006).Conclusions Our findings indicate that administration of tamsulosin has a positive effect on stent-related urinary symptoms and QoL. Further clinical research in this area is warranted to better define the role of α1-blockers in current clinical practice. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
