التفاصيل البيبلوغرافية
| العنوان: |
Progression of a Sessile Serrated Adenoma to an Early Invasive Cancer Within 8 Months. |
| المؤلفون: |
Yasuhiro Oono, Kuangi Fu, Hisashi Nakamura, Yosuke Iriguchi, Akihiko Yamamura, Yasuhiro Tomino, Johji Oda, Masaru Mizutani, Satoshi Takayanagi, Daisuke Kishi, Tomoaki Shinohara, Kozo Yamada, Jun Matumoto, Kazuhiro Imamura |
| المصدر: |
Digestive Diseases & Sciences; Apr2009, Vol. 54 Issue 4, p906-909, 4p |
| مصطلحات موضوعية: |
ADENOMA, POLYPS, COLON cancer, MORPHOLOGY, HISTORY of diseases, TUMORS |
| مستخلص: |
Abstract Recent studies suggest that serrated polyps, including hyperplastic polyps, traditional serrated adenomas, and sessile serrated adenomas, may be morphologically and genetically distinct and linked to microsatellite unstable colorectal cancers, and thus the concept of a hyperplastic polyp–serrate adenoma–carcinoma pathway has been suggested. Furthermore, it has been suggested that transformation from serrated polyps to invasive cancers can be rapid and occurs when the lesions are small; however, direct evidence for this issue is scant. We herein describe a case of a sessile serrated adenoma showing rapid transformation into a submucosal invasive carcinoma with remarkable morphological change in a short period of 8 months. This case is unique and suggestive, as it provided information about the natural history of a sessile serrated adenoma. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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