التفاصيل البيبلوغرافية
العنوان: |
Ambient Air Pollution and Cardiovascular Malformations in Atlanta, Georgia, 1986-2003. |
المؤلفون: |
Matthew J. Strickland, Mitchel Klein, Adolfo Correa, Mark D. Reller, William T. Mahle, Tiffany J. Riehle-Colarusso, Lorenzo D. Botto, W. Dana Flanders, James A. Mulholland, Csaba Siffel, Michele Marcus, Paige E. Tolbert |
المصدر: |
American Journal of Epidemiology; Apr2009, Vol. 169 Issue 8, p1004-1004, 1p |
مصطلحات موضوعية: |
AIR pollution, PHYSIOLOGICAL effects of pollution, DURATION of pregnancy, CARDIOVASCULAR diseases risk factors, COHORT analysis, PARTICULATE matter, TRANSPOSITION of great vessels, PATENT ductus arteriosus, CONFIDENCE intervals |
مصطلحات جغرافية: |
ATLANTA (Ga.), GEORGIA |
مستخلص: |
Associations between ambient air pollution levels during weeks 3â7 of pregnancy and risks of cardiovascular malformations were investigated among the cohort of pregnancies reaching at least 20 weeksâ gestation that were conceived during January 1, 1986âMarch 12, 2003, in Atlanta, Georgia. Surveillance records obtained from the Metropolitan Atlanta Congenital Defects Program, which conducts active, population-based surveillance on this cohort, were reviewed to classify cardiovascular malformations. Ambient 8-hour maximum ozone and 24-hour average carbon monoxide, nitrogen dioxide, particulate matter with an average aerodynamic diameter of 10), and sulfur dioxide measurements were obtained from centrally located stationary monitors. Temporal associations between these pollutants and daily risks of secundum atrial septal defect, aortic coarctation, hypoplastic left heart syndrome, patent ductus arteriosus, valvar pulmonary stenosis, tetralogy of Fallot, transposition of the great arteries, muscular ventricular septal defect, perimembranous ventricular septal defect, conotruncal defects, left ventricular outflow tract defect, and right ventricular outflow defect were modeled by using Poisson generalized linear models. A statistically significant association was observed between PM10 and patent ductus arteriosus (for an interquartile range increase in PM10 levels, risk ratioâ=â1.60, 95% confidence interval: 1.11, 2.31). Of the 60 associations examined in the primary analysis, no other significant associations were observed. [ABSTRACT FROM AUTHOR] |
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قاعدة البيانات: |
Complementary Index |