التفاصيل البيبلوغرافية
| العنوان: |
Synthesis of surface enhanced Raman scattering active magnetic nanoparticles for cell labeling and sorting. |
| المؤلفون: |
Charan, Shobhit, Kuo, Chiung Wen, Kuo, Yu-Wei, Singh, Narendra, Drake, Philip, Lin, Yuh-Jiuan, Tay, Lilin, Chen, Peilin |
| المصدر: |
Journal of Applied Physics; Apr2009, Vol. 105 Issue 7, p07B310-07B310-3, 3p, 2 Black and White Photographs, 2 Graphs |
| مصطلحات موضوعية: |
PARAMAGNETISM, NANOPARTICLES, CELL separation, SURFACE enhanced Raman effect, THIOLS |
| مستخلص: |
Here we report the synthesis of the magnetic nanocomposite nanoparticles with Fe3O4 core and silver shell for cell imaging and separation. When the magnetic nanoparticles are decorated with surface enhanced Raman scattering (SERS) active molecules, they can be used for cell separation with unique optical signature. In this experiment, commercially available superparamagnetic nanoparticles (fluidMAG) with 50 nm diameter were used as the core. The shell layer was produced by the reduction of the silver salts. As a result of the reduction, nanocomposite magnetic nanoparticles with 60 nm diameter were obtained. To create unique SERS patterns for multiplexing, the surfaces of the nanoparticles were further modified with chloro-, bromo-, or fluorobenzenethiol. When these nanoparticles were incubated with 3T3 cells, it was found that the nanoparticles were located around the nucleus in the cytoplasm. [ABSTRACT FROM AUTHOR] |
|
Copyright of Journal of Applied Physics is the property of American Institute of Physics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Find this article in full text from Scitation.