التفاصيل البيبلوغرافية
العنوان: |
Effects of soy isoflavones on the uterus and urethra of ovariectomized rats. |
المؤلفون: |
Maria Sampaio, Paulo Cecon, Manuel de Jesus Simões, Marair Sartori, Manoel Girão |
المصدر: |
International Urogynecology Journal; Jan2010, Vol. 21 Issue 1, p111-116, 6p |
مصطلحات موضوعية: |
ISOFLAVONES, PLANT extracts, SOYBEAN, UTERUS, URETHRA, OVARIECTOMY, LABORATORY rats |
مستخلص: |
Abstract Objective  To evaluate the effect of soy isoflavone extract (SIE) on the uterus and urethra of castrated female rats. Methods  Ovariectomized adult virgin Wistar rats (nâ=â45) received, for 30 days: placebo (GI); SIE from day 5 of castration (GII); or day 28 of castration (GIII). A standardized SIE was administered by gavage at 125 μg genistein/g body weight/day, with a soy-free diet. Average numbers of nuclei (NU), blood vessels (BV) and collagen fibers (CF) in uterus and mid-urethra sections were compared using Dunnett and Tukey tests (95% CI). Results  Uterus: GII and GIII differed from GI in all respects; GII vs. GIII, no differences. Urethra: GIII vs. GI: no differences; GII vs. GI, differences in NU and CF; GII vs. GIII, differences in NU and CF. Conclusions  Early oral administration of SIE to ovariectomized rats reversed uterine/urethral effects of castration. [ABSTRACT FROM AUTHOR] |
|
Copyright of International Urogynecology Journal is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
قاعدة البيانات: |
Complementary Index |