التفاصيل البيبلوغرافية
| العنوان: |
An autopsy case of pancreatic and ectopic nesidioblastosis. |
| المؤلفون: |
Yasoshima, Hitoshi, Nakata, Yasuo, Ohkubo, Eriko, Matsuno, Yasuko, Sakurai, Kazunari, Kubota, Akira, Minagawa, Kyoko |
| المصدر: |
Pathology International; May2001, Vol. 51 Issue 5, p376-379, 4p |
| مصطلحات موضوعية: |
AUTOPSY, PANCREATIC diseases, PATHOLOGY |
| مستخلص: |
We report an autopsy case of pancreatic and ectopic nesidioblastosis. A five-month-old Japanese girl was born at 35 weeks gestation, and showed clinical symptoms of hyper-insulinemic hypoglycemia before death. At autopsy a tumorous nodule was observed at the portion of the jejunum, 90 cm from Treitz’s ligament. The nodule measured 30 × 20 × 20 mm. The ectopic pancreas, also revealed nesidioblastosis histologically. Immunohistologically, both nesidioblastoses were stained positive for chromogranin A, insulin, glucagon and somatostatin. The proliferating cell nuclear antigen (PCNA) and Ki-67 indices were less than 4% in the nesidioblastosis. To our knowledge, this is the first reported case of nesidioblastosis demonstrating proliferating activity with PCNA and Ki-67, and is the third reported case of nesidioblastosis arising in the pancreas and ectopic pancreas. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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