التفاصيل البيبلوغرافية
| العنوان: |
Confounding and interaction effect of Treponema denticola salivary carriage in chronic periodontitis. |
| المؤلفون: |
Martínez‐Pabón, MC, Martínez‐Gaviria, A, Isaza‐Guzmán, DM, Muskus‐López, CE, Tobón‐Arroyave, SI |
| المصدر: |
Oral Diseases; Apr2010, Vol. 16 Issue 3, p278-285, 8p, 3 Charts, 1 Graph |
| مصطلحات موضوعية: |
TREPONEMA, PERIODONTITIS, ORAL diseases, SALIVA, PATHOGENIC bacteria |
| مستخلص: |
Oral Diseases (2010) 16, 278–285 Aim: To evaluate the salivary carriage of Treponema denticola and its association with demographic variables in the etiopathogenesis of chronic periodontitis. Subjects and methods: Ninety-seven chronic periodontitis (CP) patients and a control group of 51 healthy subjects (HC) were selected. Periodontal status was assessed by criteria based on probing depth, attachment loss, extent, and severity of periodontal breakdown. A polymerase chain reaction method was used to determine the occurrence of T. denticola in saliva samples. Risk indicators for CP were assessed individually and adjusted for confounding and/or interaction using a logistic regression model. Results: Although univariate analysis revealed a positive association of age ≥30 years, smoking, and salivary carriage of T. denticola with CP, after logistic regression analysis, the association between age ≥30 years/smoking and CP persisted, whereas salivary carriage of T. denticola failed to achieve statistical significance. An interaction effect was significantly detected between these three variables. Conclusion: Although salivary carriage of T. denticola may be a risk indicator for CP, its pathogenicity should not be exclusively endorsed to its detection in saliva, but it might be associated with the synergistic biological interaction of the bacterium with some demographic characteristics of the susceptible host. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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