التفاصيل البيبلوغرافية
| العنوان: |
Recreational physical activity and risk of papillary thyroid cancer (United States). |
| المؤلفون: |
Rossing, Mary, Remler, Rachel, Voigt, Lynda, Wicklund, Kristine, Daling, Janet, Rossing, M A, Remler, R, Voigt, L F, Wicklund, K G, Daling, J R |
| المصدر: |
Cancer Causes & Control; Dec2001, Vol. 12 Issue 10, p881-885, 5p |
| مستخلص: |
Objective: Exercise has been hypothesized to influence cancer risk through a variety of mechanisms including hormonal, metabolic and immunologic effects, yet its relation with the risk of thyroid cancer has not been examined. We conducted a population-based case-control study in women aged 18-64 in three counties of western Washington State to assess the relation of recreational physical activity with risk of papillary thyroid cancer.Methods: Of 558 women with thyroid cancer of the follicular epithelium diagnosed during 1988-1994 who were identified as eligible, 468 (83.9%) were interviewed; this analysis was restricted to women with papillary histology (n = 410). Controls (n = 574) were identified by random digit dialing, with a response proportion of 73.6%. Logistic regression was used to calculate odds ratios (OR) and associated confidence intervals (CI) estimating the relative risk of papillary thyroid cancer associated with various aspects of recreational exercise.Results: Risk of thyroid cancer was reduced among women who reported that they engaged in regular recreational exercise during the 2 years before diagnosis relative to women who did not report exercise during that time period (OR = 0.76, 95% CI 0.59-0.98). A similar risk reduction was noted among women who reported having exercised regularly between ages 12 and 21 (OR = 0.83, 95% CI 0.64-1.1). However, no clear associations with aspects of recreational activity, including average hours exercised per week or weekly energy expenditure, were observed.Conclusions: These results provide some initial support for the hypothesis that physical activity may reduce risk of thyroid cancer. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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