التفاصيل البيبلوغرافية
| العنوان: |
High numbers of clonal CD19[sup +] cells in the peripheral blood of a patient with multiple myeloma. |
| المؤلفون: |
Rasmussen, Thomas, Kastrup, Jesper, Knudsen, Lene Meldgaard, Johnsen, Hans Erik |
| المصدر: |
British Journal of Haematology; Apr99, Vol. 105 Issue 1, p265-267, 3p, 2 Diagrams |
| مصطلحات موضوعية: |
CD antigens, B cells, MULTIPLE myeloma |
| مستخلص: |
Recent studies concerning the numbers of circulating clonal B cells in patients with multiple myeloma (MM) have reported conflicting data regarding the exact levels of clonal B cells and the existence of clonal cells in the CD34 compartment. In this report we show that high numbers of clonal cells with a phenotype of late-stage B cells or pre-plasma cells were present in the peripheral blood (PB) of a patient with MM. During treatment the initial high level of PB clonal cells was markedly reduced and remained low (<1%) post transplant, even after disease progression. In addition, we found that the MM clone did not include a B-progenitor population defined by CD34. [ABSTRACT FROM AUTHOR] |
|
Copyright of British Journal of Haematology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder