التفاصيل البيبلوغرافية
| العنوان: |
Serotype Specificity of Antibodies against Foot-and-Mouth Disease Virus in Cattle in Selected Districts in Uganda. |
| المؤلفون: |
Mwiine, F. N., Ayebazibwe, C., Olaho-Mukani, W., Alexandersen, S., Balinda, S. N., Masembe, C., Ademun Okurut, A. R., Christensen, L. S., Sørensen, K. J., Tjørnehøj, K. |
| المصدر: |
Transboundary & Emerging Diseases; Oct2010, Vol. 57 Issue 5, p365-374, 10p, 5 Charts, 1 Graph |
| مصطلحات موضوعية: |
FOOT & mouth disease virus, CATTLE diseases, IMMUNOGLOBULINS, CYTOSKELETAL proteins, ENZYME-linked immunosorbent assay |
| مصطلحات جغرافية: |
UGANDA |
| مستخلص: |
Uganda had an unusually large number of foot-and-mouth disease (FMD) outbreaks in 2006, and all clinical reports were in cattle. A serological investigation was carried out to confirm circulating antibodies against foot-and-mouth disease virus (FMDV) by ELISA for antibodies against non-structural proteins and structural proteins. Three hundred and forty-nine cattle sera were collected from seven districts in Uganda, and 65% of these were found positive for antibodies against the non-structural proteins of FMDV. A subset of these samples were analysed for serotype specificity of the identified antibodies. High prevalences of antibodies against non-structural proteins and structural proteins of FMDV serotype O were demonstrated in herds with typical visible clinical signs of FMD, while prevalences were low in herds without clinical signs of FMD. Antibody titres were higher against serotype O than against serotypes SAT 1, SAT 2 and SAT 3 in the sera investigated for serotype-specific antibodies. Only FMDV serotype O virus was isolated from one probang sample. This study shows that the majority of the FMD outbreaks in 2006 in the region studied were caused by FMDV serotype O; however, there was also evidence of antibodies to both SAT 1 and SAT 3 in one outbreak in a herd inside Queen Elizabeth national park area. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
