التفاصيل البيبلوغرافية
| العنوان: |
Feasibility of peripheral blood stem cell rescue as intensification in elderly patients with acute myelocytic leukaemia: a pilot study from the Gimema Group. |
| المؤلفون: |
Montillo, Marco, Tedeschi, Alessandra, Pagano, Livio, Venditti, Adriano, Ferrara, Felicetto, Fabris, Piero, Martino, Bruno, Musso, Maurizio, De Rosa, Gennaro, Specchia, Giorgina, Monaco, Michele, Sparaventi, Giovanni, Spadea, Antonio, Palmas, Angelo, Deplano, Wilma, Manna, Annunziata, Melillo, Lorella, Miraglia, Eustachio, Mirto, Salvatore, Mandelli for the Gimema Group, Franco |
| المصدر: |
British Journal of Haematology; Oct2000, Vol. 111 Issue 1, p334-337, 4p, 1 Diagram, 1 Graph |
| مصطلحات موضوعية: |
MYELOID leukemia, DISEASES in older people, STEM cells |
| مستخلص: |
Elderly patients with untreated acute myeloid leukaemia (AML, n = 47) tested the feasibility of out-patient consolidation therapy and post-consolidation treatment (for patients aged < 71 years) with autologous peripheral blood stem cell transplantation (APBSCT). Overall, 13 patients out of 24 (51%) who achieved complete remission (CR) were eligible for further treatment after consolidation. Five patients were primed with granulocyte colony stimulating factor (G-CSF); a suitable number of CD34+ cells were harvested in three patients and were actually autotransplanted. The toxicity of APBSCT was negligible. Psychosocial problems impaired treatment of some patients on an out-patient basis. Resistant disease, toxicity and logistic problems reduced the number of patients to whom this procedure could actually be applied. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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