التفاصيل البيبلوغرافية
| العنوان: |
Lingering prenatal effects of the 1918 influenza pandemic on cardiovascular disease. |
| المؤلفون: |
Mazumder, B., Almond, D., Park, K., Crimmins, E. M., Finch, C. E. |
| المصدر: |
Journal of Developmental Origins of Health & Disease; 2009, Vol. 1 Issue 1, p26-34, 9p |
| مستخلص: |
Prenatal exposure to the 1918 influenza pandemic (Influenza A, H1N1 subtype) is associated with ⩾20% excess cardiovascular disease at 60 to 82 years of age, relative to cohorts born without exposure to the influenza epidemic, either prenatally or postnatally (defined by the quarter of birth), in the 1982–1996 National Health Interview Surveys of the USA. Males showed stronger effects of influenza on increased later heart disease than females. Adult height at World War II enlistment was lower for the 1919 birth cohort than for those born in adjacent years, suggesting growth retardation. Calculations on the prevalence of maternal infections indicate that prenatal exposure to even uncomplicated maternal influenza may have lasting consequences later in life. These findings suggest novel roles for maternal infections in the fetal programming of cardiovascular risk factors that are independent of maternal malnutrition. [ABSTRACT FROM PUBLISHER] |
|
Copyright of Journal of Developmental Origins of Health & Disease is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
